SP353HOW TO ASSESS THE EFFICACY OF PHOSPHATE BINDERS

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How to assess the efficacy of phosphate binders.

BACKGROUND AND AIMS The efficacy of phosphate binders is difficult to be estimated clinically. This study analyzes the changes in serum phosphate and urinary phosphate excretion after the prescription of phosphate binders (PB) in patients with chronic kidney disease stage 4-5 pre-dialysis, and the usefulness of the ratio between total urinary phosphate and protein catabolic rate (Pu/PCR) for es...

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Increased cardiovascular morbidity and mortality has been associated with the hyperphosphatemia seen in patients with end-stage chronic kidney disease (CKD). Oral phosphate binders are prescribed in these patients to prevent intestinal absorption of dietary phosphate and reduce serum phosphate. In prospective observational cohorts they have shown to decrease all-cause and cardiovascular mortali...

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ژورنال

عنوان ژورنال: Nephrology Dialysis Transplantation

سال: 2017

ISSN: 0931-0509,1460-2385

DOI: 10.1093/ndt/gfx147.sp353